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KMID : 0613820050150020304
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Journal of Life Science
2005 Volume.15 No. 2 p.304 ~ p.310
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Effect of Herbicide Paraquat on NAD(H)-Redox-cycle
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Kim Mi-Lim
Choi Kyung-Ho
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Abstract
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This study was carried out to investigate the effect of herbicide paraquat (1,1-dimethyl-4,4-bipyridilium dichloride) on the electron transport system of the cell.When actively growing cells of bacteria were exposed to the 1.0 mM paraquat, more than 50% of the cells were killed at 0 hour. But specific activities of superoxide dismutase (SOD) were not changed at 0 hour of paraquat treatment. Oxido-reductions of NAD (H) by the suspension of bacterial membtane, rat mithochondria and NAD-dependent dehydrogenase were accelerated by paraquat treatment.
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